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Int J Neuropsychopharmacol ; 24(9): 703-709, 2021 09 21.
Article in English | MEDLINE | ID: covidwho-1429234

ABSTRACT

BACKGROUND: Psychiatric patients are perceived to be especially vulnerable during a pandemic, as it increases stress and uncertainty. Several current publications have considered obsessive-compulsive disorder (OCD) patients to be particularly vulnerable during the coronavirus disease 2019 (COVID-19), and clinicians were advised to adjust treatments accordingly. The purpose of this study was to evaluate the 2- and 6-month impacts of COVID-19 on the symptom severity of OCD patients. METHODS: A cohort of OCD patients actively treated with Exposure and Response Prevention (ERP) combined with pharmacological treatment was evaluated as part of their regular psychiatric assessment twice: 113 patients were evaluated at their 2-month follow-up and 90 patients (from that cohort) were evaluated at their 6-month follow up. RESULTS: Obsessive-compulsive symptom deterioration was not present in 84% of the patients at the 2-month follow-up and 96% of the patients at the 6-month follow-up. The results were also replicated in the OCD subgroup that included patients with contamination (washers) and illness obsessions, who were believed to be particularly vulnerable considering their obsessional content. CONCLUSIONS: OCD patients (including those with obsessions related to contamination and health) who were under active ERP and pharmacological treatment did not experience exacerbated symptoms during COVID-19 at their 2- and 6-month follow-ups.


Subject(s)
COVID-19 , Obsessive-Compulsive Disorder/physiopathology , Obsessive-Compulsive Disorder/therapy , Outcome Assessment, Health Care , Symptom Flare Up , Adolescent , Adult , Aged , Cognitive Behavioral Therapy , Dopamine D2 Receptor Antagonists/therapeutic use , Female , Follow-Up Studies , Humans , Implosive Therapy , Male , Middle Aged , Obsessive-Compulsive Disorder/drug therapy , Selective Serotonin Reuptake Inhibitors/therapeutic use , Young Adult
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